Postdoctoral Associate, Lab of Viral Replication, Pathogenesis, and Immunity, UMass Medical School   Candidates are invited to apply for a post-doctoral position to study pathogenic viruses, including SARS-CoV-2, Ebola virus, and HIV-1. Research topics include basic mechanisms of virus replication, interaction between the virus and host factors, virus evolution, innate immune detection, gene function and chromatin profiling in primary human immune cells. Please see recent publications at: https://pubmed.ncbi.nlm.nih.gov/?term=luban+j&sort=date   Qualifications: Education, experience and skills required for consideration:   - Ph.D. in biochemistry, molecular biology, immunology, virology, or bioinformatics, or M.D. with equivalent experience - Evidence of creativity and excitement about applying skills towards solving biological problems - Highly collegial, works well as a team member, and embraces diversity as an essential strength of research - Excellent analytical skills and independent judgement - Strong written and verbal communication skills - Meticulous record keeping, proficiency with databases, and computational skills   To Apply:   Applicants should submit the following materials by email to Dr. Jeremy Luban at jeremy.luban@umassmed.edu: a letter describing current research activities and your interest in this position, a CV (including a complete list of publications), and contact information for three references, one of which should be your Ph.D. advisor. We encourage all qualified applicants to apply. Diversity is a core value of our campus, the only public medical school in the Commonwealth of Massachusetts.

The Horae Gene Therapy Center of the University of Massachusetts Chan Medical School invites applications for a postdoctoral researcher position to develop AAV-based gene therapy technologies using genome editing and RNA-based methods.   Applicants should have a PhD degree in relevant areas such as molecular biology, RNA biology, biochemistry, and virology. Applicants of diverse research background are encouraged to apply, such as neuroscience, mouse genetics, bioengineering, and cell biology. Applicants highly skilled in molecular cloning, mouse work, deep sequencing and data analysis (Illumina, PacBio, Nanopore), are preferred. Applicants must also have the ability to work independently, coordinate multiple projects and activities concurrently. Strong writing, verbal, and interpersonal skills are required.  Candidates should be highly organized, hard-working and motivated to respond to the changes within the rapidly evolving field of gene therapy. We offer excellent training opportunities and a competitive salary depending on experience and track records.For further information, please send cover letter, CV and contact information of three references to:     Dan Wang, Ph.D. Assistant Professor Horae Gene Therapy Center & RNA Therapeutics Institute University of Massachusetts Chan Medical School AS6-2061, 368 Plantation Street Worcester, MA 01605   Phone: (774)-455-4574 E-mail:  dan.wang@umassmed.edu Lab website: https://www.umassmed.edu/wanglab/   UNIVERSITY OF MASSACHUSETTS CHAN MEDICAL SCHOOL The University of Massachusetts Chan Medical School, one of the fastest growing academic health centers in the country, has built a reputation as a world-class research institution, consistently producing noteworthy advances in clinical and basic research.  As a research institution, UMass Chan attracts nearly $300 million annually in funding from government agencies, private groups, and philanthropic organizations.  Faculty members are nationally recognized authorities in areas ranging from cancer to diabetes to genetics and are regularly honored for their work.   As an equal opportunity and affirmative action employer, UMass Chan recognizes the power of a diverse community and encourages applications from individuals with varied experiences, perspectives and backgrounds

GENERAL SUMMARY OF POSITION:   Under the direction of the Principal Investigator or designee, the Research Associate III performs a variety of complex research experiments.    

The Tai and Gao labsof the Horae Gene Therapy Center at the UMass Chan Medical School are inviting applications for postdoctoral positions to pursue multiple research topics that encompass: gene therapy using AAV vectors, RNA therapy, gene editing, immunology, virology, and AAV vector development.   Applicants should have a PhD degree or an MD with post-graduate scientific training, and at least three years of research experience in relevant areas such as Molecular Biology, RNA biology, Biochemistry, animal modeling, Immunology, Gene Therapy, Cell Therapy, Bioengineering, Neuromuscular Biology, Cell Biology, and Virology.   Applicants with backgrounds in molecular biology, mouse work, NHP work, gene editing, microscopy, human and mouse genetics, next-gen sequencing, bioinformatics, single-cell sequencing, or protein/structural biology are preferred.    Applicants must also have the ability to work independently and coordinate multiple projects, concurrently. Strong writing, verbal, and interpersonal skills are required.     Candidates should be highly organized, hard-working, and motivated to respond to changes within the rapidly evolving field of gene therapy. We offer excellent training opportunities and a competitive salary depending on experience and track record.If you have any of the above attributes and skill sets, and believe you are a good fit for our research program, please send a cover letter, your CV, and contact information of three references to:   Phillip Tai, Ph.D. Assistant Professor, Horae Gene Therapy Center and Vector Core E-mail: phillip.tai2@umassmed.edu   The UMass Chan Medical School, one of the fastest growing academic health centers in the country, has built a reputation as a world-class research institution, consistently producing noteworthy advances in clinical and basic research.  As a research institution, UMMS attracts nearly $300 million annually in funding from government agencies, private groups, and philanthropic organizations.  Faculty members are nationally recognized authorities in areas ranging from cancer to diabetes to genetics and are regularly honored for their work.   As an equal opportunity and affirmative action employer, UMass Chan recognizes the power of a diverse community and encourages applications from individuals with varied experiences, perspectives and backgrounds

GENERAL SUMMARY OF POSITION:     Under the general direction of the Principal Investigator or designee, the Research Associate IV performs a variety of complex research experiments and is responsible for overseeing laboratory operations within the Department.    

We are seeking an outstanding individual for a fully funded postdoctoral position in the laboratories of Dale Greiner, Ph.D. and Michael Brehm, Ph.D. Our laboratories are developing a number of cutting-edge humanized mouse models to study type 1 diabetes. Our research interests include; 1) effector functions of human autoreactive T cells, 2) interactions between autoreactive T cells and human pancreatic beta cells and 3) identifying immune therapeutics that suppress the destruction of human beta cells by autoreactive T cells. To address these interests, we use a number of approaches including immunological, cellular, molecular and genomic. In addition to learning multidisciplinary approaches to study human type 1 diabetes, the candidate will have opportunities for career development in both academic and private sectors. To Apply: Interested candidates should email a cover letter, CV, and 3 references to: Michael Brehm at Michael.Brehm@umassmed.edu

POSITION SUMMARY:   A Research Associate position is available at the Mass Spectrometry Facility at The University of Massachusetts Chan Medical School. Under the general direction of the Principal Investigator or designee, the Research Associate IV performs a variety of complex research experiments and is responsible for overseeing laboratory operations within the Department. Affiliated with the Department of Biochemistry and Molecular Biotechnology, the Facility supports projects in basic and translational science across a diverse range of applications in proteomics, structural biology, metabolomics, small molecule quantitation, and mass spectrometry imaging. There are nine mass spectrometry platforms including four Orbitraps (Thermo Fusion Lumos w/ ETD and FAIMS, Q Exactive HF-X, Q Exactive and Orbitrap Velos Pro), a Q-TOF (Waters Synapt G2-Si) and two triple quadrupoles (Waters Xevo TQ-XS and Thermo TSQ Quantiva), all located in a spacious 5,000 sq. ft facility. We are looking for a highly motivated individual to contribute to a wide and diverse range of projects utilizing quantitative proteomics AND/OR targeted/untargeted metabolomics approaches to solve important biological problems in basic and translational science.   When submitting your resume, please include a cover letter detailing your interest in the position, your experience with proteomics or metabolomics and how the specifics of the opportunity fit with your career goals.  

GENERAL SUMMARY OF POSITION: Under the general direction of the Director of the Power Plant or designee, the High Voltage Electrician/Co- Gen Engineer is responsible for the operation, repair and maintenance of all electrical systems, motors, controls, high voltage (13,800 volts) generation, switching and distribution equipment and systems. Performs all electrical work as required, and operates boilers, turbine generators, turbo motor compressors, and all related auxiliaries when required. Performs repairs to boiler, turbo generators, pumps, etc.