University of Massachusetts Medical School

Research Associate I - $2,000 Sign on bonus

Minimum Salary US-MA-Worcester
Job Location 2 months ago(2/1/2023 11:55 AM)
Requisition Number
2023-42720
# of Openings
1
Posted Date
Day
Shift
Exempt
Exempt/Non-Exempt Status
Non Union Position -W60- Non Unit Professional

Overview

POSITION SUMMARY: 

The Cantor laboratory focuses on understanding how tumor suppressor proteins function to maintain genomic integrity and suppress cancer. In particular, we focus on the hereditary breast and ovarian cancer genes, BRCA1, BRCA2 and the BRCA1-associated helicase, FANCJ (BACH1/ BRIP1). Bi-allelic loss of these genes also causes Fanconi anemia (FA), a rare chromosomal instability and cancer syndrome. Our work on FANCJ revealed that DNA repair defects underlie both hereditary breast cancer and FA. Currently, we are employing biochemical and whole-genome screening technologies, to uncover mechanisms regulating DNA repair choice and how cancer cells evade toxic chemotherapies.  MCCB Faculty Page - Sharon Cantor, Ph.D.

 

Responsibilities

ESSENTIAL FUNCTIONS:

  • Perform laboratory experiments and may be responsible for a single research project
  • Utilize all software relevant to experiment and equipment used
  • Interpret data, form conclusions and decide on next steps under the direction of the PI or designee
  • Maintain accurate records, may modify protocols with the approval of the PI or designee
  • Review literature, publications and grants relevant to assigned projects
  • Record results according to established lab, sponsor & university protocol
  • Assist with performing data analysis and/or mathematical computations
  • Maintain a detailed lab notebook according to lab practice
  • Present findings at lab/group meetings
  • Monitor laboratory supply levels and order as noted
  • Prepare and label buffers, media, solutions, etc.
  • Assist with and comply with all safety regulation and infection control standards
  • Train on IACUC, IRB, EHS, Radiation safety protocols
  • Comply with all applicable state, federal university, and sponsor policies and agreements
  • Provide support with identifying problems and challenges, propose resolutions, implement appropriate solutions
  • Provide support with drafting standard operation procedures in compliance to EHS regulation specific for the lab
  • Perform other duties as required

Qualifications

REQUIRED QUALIFICATIONS:

  • Bachelor’s degree in Biological or Natural Science, or equivalent experience
  • Basic understanding of lab safety and protocols
  • Knowledge of Microsoft Office products
  • Ability to analyze data in a quantitative and objective manner.
  • Ability to work in a team environment

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