University of Massachusetts Medical School

Research Associate- Molecular Cell & Cancer Biology

Minimum Salary US-MA-Worcester
Job Location 2 months ago(12/18/2020 10:01 AM)
Requisition Number
2020-36255
# of Openings
1
Posted Date
Day
Shift
Exempt
Exempt/Non-Exempt Status
Non Union Position -W60- Non Unit Professional

Overview

GENERAL SUMMARY OF POSITION:  

Under the direction of the Principal Investigator or Designee, the Research Associate performs a variety of complex research experiments.

 

 

Responsibilities

MAJOR RESPONSIBILITIES:

  • Conducts in-depth analysis of research experiments
  • Performs complex laboratory experiments
  • Interprets data, forms conclusion, and decides on and plans next experiments to be done with a high degree of independence
  • Compiles and analyzes data and performs computations using image analysis software, spreadsheets, graphing, and curve fitting software
  • May modify protocols and be responsible for a single, independent research project
  • Assists in writing the text of scientific publications and grants.  Reviews literature
  • Trains new laboratory personnel, students, and collaborators
  • Maintains laboratory supplies and equipment
  • Complies with all safety and infection control standards
  • Perform other duties as required.

Qualifications

REQUIRED QUALIFICATIONS:  

  • Bachelor’s degree in Biological Sciences, or equivalent experience
  • 1 year relevant research experience
  • Knowledge of Microsoft Office products
  • Strong ability to analyze complex visual data in a quantitative and objective manner
  • Judgment and action skills required to solve commonly encountered problems

PREFERRED QUALIFICATIONS:

  • Experience with Adobe Illustrator, Photoshop and PowerPoint to prepare publication quality figures considered a plus.

SUPERVISION RECEIVED:

Under the direction of the Principal Investigator, or designee

 

SUPERVISION EXERCISED: 

May functionally supervise Lab Technicians and Aides

 

ENVIRONMENTAL WORKING CONDITIONS:

Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens. 

Additional Information

Summary of Position

We currently have an opening for a Research Associate to join the laboratory of Dr. Michelle Kelliher at the University of Massachusetts Medical Center. The Kelliher lab studies how leukemia develops using genetically engineered mouse models and patient derived xenografts. We are focused on understanding the molecular and cellular basis of chemoresistance and relapse in an effort to develop novel therapeutic approaches. Our lab uses innovative mouse modeling approaches and single cell sequencing and chromatin accessibility methods to identify features of leukemic stem or initiating cells thought to mediate relapse. This position offers opportunities for career development, including possibly designing and executing independent experiments which could lead to publication.

Responsibilities

  • Work collaboratively to assist Postdoctoral fellows and graduate students with research projects
  • Perform a variety of laboratory experiments using both routine and special techniques, including:
    • Molecular biology procedures such as DNA purification, PCR, gel electrophoresis, cloning, qRT-PCR, and Western blotting
    • Cell culture work 
    • Mouse colony management, breeding, and genotyping
    • Mouse experiments, injections and organ harvesting
    • Routine histology, immunohistochemistry, and immunofluorescence
    • Flow cytometry analysis 
  • Collect, record, and analyze data
  • Assist in the training of others
  • Write and provide input to improve current procedures, protocols, and/or methods
  • Prepare laboratory reagents, buffers, media, and other general lab stocks
  • Assist with lab organizational tasks, including lab equipment setup and lab supply ordering and purchasing

 Job Requirements

  • Bachelor's Degree in Biology or a related scientific discipline
  • A minimum of two years of experience in a research laboratory setting, with experience in molecular biology and cell culture techniques preferred 
  • Mouse experience is highly desired but not required
  • Self-motivated, detail-oriented, and able to perform complex tasks effectively and independently with general instruction
  • Ability to work in a team-focused environment
  • Excellent communication and computer skills

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