University of Massachusetts Medical School

  • Research Associate II

    Minimum Salary US-MA-Worcester
    Job Location 9 months ago(12/3/2018 8:28 AM)
    Requisition Number
    # of Openings
    Posted Date
  • Overview



    Our group studies how regulatory elements establish cell specific gene expression patterns. Our goal is to reliably estimate the impact of regulatory mutations on immune and autoimmune disease. To this end we combine innate immune murine and human in-vitro models and ongoing clinical collaborations. Our laboratory actively develops both computational and experimental methods to map and functional characterize 3-dimensional regulatory interactions, build models that incorporate these interaction maps to predict gene expression and applies these models to clinical data.


    We seek a highly motivated individual to lead our experimental operation. In this role you will mentor graduate students and work together with computational biologists in the design, analysis and interpretation of methods to map and understand gene regulatory elements.


    Under the general direction of the Principal Investigator or designee, the Research Associate II performs a variety of complex research experiments and is responsible for overseeing laboratory operations within the Department.





    • Perform complex laboratory experiments and conduct in-depth analysis of research experiments
    • Write standard operating procedures, schedule work, analyze data, maintain accurate records, and write reports
    • Report the status of projects and observations to the Department Chair
    • Ensure departmental computer resources remain functional and provide on-site support to Investigators as requested
    • Design and execute protocols and experiments, modify protocols as needed, and may be responsible for own research project
    • Manage laboratory research staff
    • Responsible for overall laboratory organization including oversight of safety protocols and the maintenance of related records 
    • May assist with budget and/or operational aspects of grant and contract proposals
    • Long-range planning for laboratory and departmental equipment maintenance and replacement. Assist in procurement of departmental equipment. Responsible for physical inventory of all equipment, and maintaining records of all equipment acquired, moved off-site, or discarded
    • Oversee and coordinate the use of centralized departmental facilities
    • Work with Facilities Engineering, Environmental Health and Safety, and Radiation Safety to ensure department facilities and laboratories are in compliance with federal, state and institutional regulations
    • Assist in writing the text of scientific publications and grants.  Review literature
    • Oversee and assist in the training of new laboratory personnel, students, and collaborators
    • Comply with all safety and infection control standards
    • Perform other duties as required





    • Bachelor’s degree in the Biological Sciences, or equivalent experience
    • 5 years of relevant research experience
    • Knowledge of Microsoft Office products
    • Strong ability to analyze complex visual data in a quantitative and objective manner
    • Judgment and action skills required to solve commonly encountered problems


    Additional Information


    Under the direction of the Principal Investigator, or designee



    Supervise aides, technicians, and associates



    Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens


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