University of Massachusetts Medical School

Research Associate

US-MA-Worcester
2 months ago
Requisition Number
2017-29706
# of Openings
1
Shift
Day
Exempt/Non-Exempt Status
Exempt
Union Code
Non Union Position -W60- Non Unit Professional

Overview

GENERAL SUMMARY OF POSITION:  

Under supervision of the Principal Investigator or designee, assists in the development of protocols to execute/perform complex research experiments in analysis and treatment of animal models of ALS, also known as Lou Gehrig's disease.

 

Major Responsibilities include-

Conducts research experiments and may assist in the training of others in:

  • Genotyping transgenic mice, which includes DNA and RNA extraction from mouse tails and other tissues, restriction digestion, PCR, real time PCR and electrophoresis with agarose and polyacrylamide gels.
  • Analysis of phenotypes and treatment outcomes of mouse models for ALS, which involves breeding and monitoring animals for the disease progression, behavioral tests and detailed record keeping.
  • Analysis of pathology of mouse models for ALS, which involves tissue harvesting, DNA, RNA, protein extraction, protein gel electrophoresis, Western blotting, tissue sectioning and immunohistochemistry and immunofluorescence staining.
  • The general requirement will also include writing standard operating procedures, scheduling work, analyzing data, writing reports, maintaining inventory, complying with all safety and infection control standards and working with Principal Investigator and other laboratory personnel harmoniously, cooperatively and effectively.

 

Responsibilities

MAJOR RESPONSIBILITIES:

  • Conducts in-depth analysis of research experiments
  • Performs complex laboratory experiments
  • Interprets data, forms conclusion, and decides on and plans next experiments to be done with a high degree of independence
  • Compiles and analyzes data and performs computations using image analysis software, spreadsheets, graphing, and curve fitting software
  • May modify protocols and be responsible for a single, independent research project
  • Assists in writing the text of scientific publications and grants.  Reviews literature
  • Trains new laboratory personnel, students, and collaborators
  • Maintains laboratory supplies and equipment
  • Complies with all safety and infection control standards
  • Perform other duties as required.

Qualifications

REQUIRED QUALIFICATIONS:  

  • Bachelor’s degree in Biological Sciences, or equivalent experience
  • 1 year relevant research experience
  • Knowledge of Microsoft Office products
  • Strong ability to analyze complex visual data in a quantitative and objective manner
  • Judgment and action skills required to solve commonly encountered problems

PREFERRED QUALIFICATIONS:

  • Prior working background with Molecular biology, biochemistry and histology.
  • Experience in animal experiments, routine laboratory operations and techniques of molecular biology and histology

 

SUPERVISION RECEIVED:

Under the direction of the Principal Investigator, or designee

 

SUPERVISION EXERCISED: 

May functionally supervise Lab Technicians and Aides

 

ENVIRONMENTAL WORKING CONDITIONS:

Wet chemistry laboratory, and may require appropriate contact with biohazards, radionuclides, toxins, animals, and human specimens. 

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