GENERAL SUMMARY OF POSITION:
A Research Specialist position is available in the Miller laboratory to investigate and extend the scope of bioluminescence for non-invasive imaging of specific biological processes and disease states in live animals. Work in the lab is inherently multi-disciplinary and may include protein engineering, mouse imaging, culture of multiple cell lines, vector design, enzyme assays, chemical synthesis, and immunohistochemistry of tissues. Examples of recent lab efforts include bioluminescence imaging of gene expression and enzymatic activity in the brain [Nature Methods 11, 393 (2014); JACS 137, 8684 (2015); Angewandte Chemie 55, 4943 (2016)], detection of latent luciferase activity in fruit flies [PNAS 111, 4443 (2014)], and the development of new selective mutant luciferases and synthetic luciferin substrates [JACS 136, 13277 (2014); Angewandte Chemie 55, 4943 (2016)]. Motivated and inherently curious critical thinkers with experience in molecular biology, cell biology, biochemistry, neuroscience, and animal studies are particularly encouraged to apply.
Under the direction of the Principal Investigator or designee, the Research Specialist conducts and evaluates scientific research in a laboratory, clinic, and/or teaching environment (hereafter referred to as “laboratory”) Employees in this position understand the context and implications of the research in order to apply and interpret theoretical knowledge necessary to conduct research in one or more scientific disciplines. The range of duties includes, but is not limited to: project planning, data collection and analysis, project management, preparing reports, and communication and instruction. Work may include the training and supervision of staff, students and others in performing specific techniques/experiments.
Under the direction of the Principal Investigator or designee
May direct other lab staff and students.
ENVIRONMENTAL WORKING CONDITIONS:
The position involves work in a laboratory and may require appropriate contact with biohazards, radionuclides, toxins, animals and human specimens