University of Massachusetts Medical School

Research Specialist

7 months ago
Requisition Number
# of Openings
Exempt/Non-Exempt Status




A Research Specialist position is available in the Miller laboratory to investigate and extend the scope of bioluminescence for non-invasive imaging of specific biological processes and disease states in live animals. Work in the lab is inherently multi-disciplinary and may include protein engineering, mouse imaging, culture of multiple cell lines, vector design, enzyme assays, chemical synthesis, and immunohistochemistry of tissues. Examples of recent lab efforts include bioluminescence imaging of gene expression and enzymatic activity in the brain [Nature Methods 11, 393 (2014); JACS 137, 8684 (2015); Angewandte Chemie 55, 4943 (2016)], detection of latent luciferase activity in fruit flies [PNAS 111, 4443 (2014)], and the development of new selective mutant luciferases and synthetic luciferin substrates [JACS 136, 13277 (2014); Angewandte Chemie 55, 4943 (2016)]. Motivated and inherently curious critical thinkers with experience in molecular biology, cell biology, biochemistry, neuroscience, and animal studies are particularly encouraged to apply.


Under the direction of the Principal Investigator or designee, the Research Specialist conducts and evaluates scientific research in a laboratory, clinic, and/or teaching environment (hereafter referred to as “laboratory”)  Employees in this position understand the context and implications of the research in order to apply and interpret theoretical knowledge necessary to conduct research in one or more scientific disciplines. The range of duties includes, but is not limited to: project planning, data collection and analysis, project management, preparing reports, and communication and instruction.  Work may include the training and supervision of staff, students and others in performing specific techniques/experiments.





  • Conduct various complex tests, experiments and/or procedures following protocols of assigned research projects
  • Apply and interpret theoretical knowledge necessary to conduct research in one or more scientific disciplines
  • Identify potential problems, recommend and implement solutions, and collaborate in the development of new techniques
  • Monitor and collect data as required by research protocols
  • Maintain appropriate documentation of research results, as required by research protocols.
  • Search literature demonstrating an understanding of scientific, experimental and/or research theory to assist in the design of methods, procedures, and techniques
  • May configure, operate and/or maintain specialized equipment
  • May use software applications to assemble, manipulate, format and/or perform statistical analysis of data
  • May train others in laboratory techniques and the use of laboratory equipment
  • May assist in writing grants, progress reports, and manuscripts
  • Performs other duties as assigned.





  • Ph.D. and 1 year of postdoctoral experience
  • Recent bench work experience required
  • Ability to prepare research reports
  • Good verbal and written communication skills
  • Demonstrated ability to understanding scientific, experimental and or research theory


  • Applicants must have a Ph.D. in Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, or related fields.
  • Applicants should have experience in several of the following areas: molecular cloning, cell culture, mouse husbandry and disease models, immunohistochemistry, neuroscience, imaging, and biochemistry.



Under the direction of the Principal Investigator or designee



May direct other lab staff and students. 



The position involves work in a laboratory and may require appropriate contact with biohazards, radionuclides, toxins, animals and human specimens


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